Dogs were the first domestic animal, but little is known about their population history and to what extent it was linked to humans. We sequenced 27 ancient dog genomes and found that all dogs share a common ancestry distinct from present-day wolves, with limited gene flow from wolves since domestication but substantial dog-to-wolf gene flow. By 11,000 years ago, at least five major ancestry lineages had diversified, demonstrating a deep genetic history of dogs during the Paleolithic. Coanalysis with human genomes reveals aspects of dog population history that mirror humans, including Levant-related ancestry in Africa and early agricultural Europe. Other aspects differ, including the impacts of steppe pastoralist expansions in West and East Eurasia and a near-complete turnover of Neolithic European dog ancestry.
Keywords:
prehistoric dogs
Source:
Science, 2020, 370, 6516, 557-563
Publisher:
Amer Assoc Advancement Science, Washington
Funding / projects:
SciLifeLab National Projects
Erik Philip Sorensen Foundation
Francis Crick Institute from Cancer Research UK [FC001595]
UK Medical Research CouncilUK Research & Innovation (UKRI)Medical Research Council UK (MRC)
TY - JOUR
AU - Bergstrom, Anders
AU - Frantz, Laurent
AU - Schmidt, Ryan
AU - Ersmark, Erik
AU - Lebrasseur, Ophelie
AU - Girdland-Flink, Linus
AU - Lin, Audrey T.
AU - Stora, Jan
AU - Sjogren, Karl-Goran
AU - Anthony, David
AU - Antipina, Ekaterina
AU - Amiri, Sarieh
AU - Bar-Oz, Guy
AU - Bazaliiskii, Vladimir I.
AU - Bulatović, Jelena
AU - Brown, Dorcas
AU - Carmagnini, Alberto
AU - Davy, Tom
AU - Fedorov, Sergey
AU - Fiore, Ivana
AU - Fulton, Deirdre
AU - Germonpre, Mietje
AU - Haile, James
AU - Irving-Pease, Evan K.
AU - Jamieson, Alexandra
AU - Janssens, Luc
AU - Kirillova, Irina
AU - Horwitz, Liora Kolska
AU - Kuzmanović-Cvetković, Julka
AU - Kuzmin, Yaroslav
AU - Losey, Robert J.
AU - Loznjak-Dizdar, Daria
AU - Mashkour, Marjan
AU - Novak, Mario
AU - Onar, Vedat
AU - Orton, David
AU - Pasaric, Maja
AU - Radivojević, Miljana
AU - Rajković, Dragana
AU - Roberts, Benjamin
AU - Ryan, Hannah
AU - Sablin, Mikhail
AU - Shidlovskiy, Fedor
AU - Dimitrijević, Ivana
AU - Tagliacozzo, Antonio
AU - Trantalidou, Katerina
AU - Ullen, Inga
AU - Villaluenga, Aritza
AU - Wapnish, Paula
AU - Dobney, Keith
AU - Gotherstrom, Anders
AU - Linderholm, Anna
AU - Dalen, Love
AU - Pinhasi, Ron
AU - Larson, Greger
AU - Skoglund, Pontus
PY - 2020
UR - http://rai.ai.ac.rs/handle/123456789/353
AB - Dogs were the first domestic animal, but little is known about their population history and to what extent it was linked to humans. We sequenced 27 ancient dog genomes and found that all dogs share a common ancestry distinct from present-day wolves, with limited gene flow from wolves since domestication but substantial dog-to-wolf gene flow. By 11,000 years ago, at least five major ancestry lineages had diversified, demonstrating a deep genetic history of dogs during the Paleolithic. Coanalysis with human genomes reveals aspects of dog population history that mirror humans, including Levant-related ancestry in Africa and early agricultural Europe. Other aspects differ, including the impacts of steppe pastoralist expansions in West and East Eurasia and a near-complete turnover of Neolithic European dog ancestry.
PB - Amer Assoc Advancement Science, Washington
T2 - Science
T1 - Origins and genetic legacy of prehistoric dogs
EP - 563
IS - 6516
SP - 557
VL - 370
DO - 10.1126/science.aba9572
ER -
@article{
author = "Bergstrom, Anders and Frantz, Laurent and Schmidt, Ryan and Ersmark, Erik and Lebrasseur, Ophelie and Girdland-Flink, Linus and Lin, Audrey T. and Stora, Jan and Sjogren, Karl-Goran and Anthony, David and Antipina, Ekaterina and Amiri, Sarieh and Bar-Oz, Guy and Bazaliiskii, Vladimir I. and Bulatović, Jelena and Brown, Dorcas and Carmagnini, Alberto and Davy, Tom and Fedorov, Sergey and Fiore, Ivana and Fulton, Deirdre and Germonpre, Mietje and Haile, James and Irving-Pease, Evan K. and Jamieson, Alexandra and Janssens, Luc and Kirillova, Irina and Horwitz, Liora Kolska and Kuzmanović-Cvetković, Julka and Kuzmin, Yaroslav and Losey, Robert J. and Loznjak-Dizdar, Daria and Mashkour, Marjan and Novak, Mario and Onar, Vedat and Orton, David and Pasaric, Maja and Radivojević, Miljana and Rajković, Dragana and Roberts, Benjamin and Ryan, Hannah and Sablin, Mikhail and Shidlovskiy, Fedor and Dimitrijević, Ivana and Tagliacozzo, Antonio and Trantalidou, Katerina and Ullen, Inga and Villaluenga, Aritza and Wapnish, Paula and Dobney, Keith and Gotherstrom, Anders and Linderholm, Anna and Dalen, Love and Pinhasi, Ron and Larson, Greger and Skoglund, Pontus",
year = "2020",
abstract = "Dogs were the first domestic animal, but little is known about their population history and to what extent it was linked to humans. We sequenced 27 ancient dog genomes and found that all dogs share a common ancestry distinct from present-day wolves, with limited gene flow from wolves since domestication but substantial dog-to-wolf gene flow. By 11,000 years ago, at least five major ancestry lineages had diversified, demonstrating a deep genetic history of dogs during the Paleolithic. Coanalysis with human genomes reveals aspects of dog population history that mirror humans, including Levant-related ancestry in Africa and early agricultural Europe. Other aspects differ, including the impacts of steppe pastoralist expansions in West and East Eurasia and a near-complete turnover of Neolithic European dog ancestry.",
publisher = "Amer Assoc Advancement Science, Washington",
journal = "Science",
title = "Origins and genetic legacy of prehistoric dogs",
pages = "563-557",
number = "6516",
volume = "370",
doi = "10.1126/science.aba9572"
}
Bergstrom, A., Frantz, L., Schmidt, R., Ersmark, E., Lebrasseur, O., Girdland-Flink, L., Lin, A. T., Stora, J., Sjogren, K., Anthony, D., Antipina, E., Amiri, S., Bar-Oz, G., Bazaliiskii, V. I., Bulatović, J., Brown, D., Carmagnini, A., Davy, T., Fedorov, S., Fiore, I., Fulton, D., Germonpre, M., Haile, J., Irving-Pease, E. K., Jamieson, A., Janssens, L., Kirillova, I., Horwitz, L. K., Kuzmanović-Cvetković, J., Kuzmin, Y., Losey, R. J., Loznjak-Dizdar, D., Mashkour, M., Novak, M., Onar, V., Orton, D., Pasaric, M., Radivojević, M., Rajković, D., Roberts, B., Ryan, H., Sablin, M., Shidlovskiy, F., Dimitrijević, I., Tagliacozzo, A., Trantalidou, K., Ullen, I., Villaluenga, A., Wapnish, P., Dobney, K., Gotherstrom, A., Linderholm, A., Dalen, L., Pinhasi, R., Larson, G.,& Skoglund, P.. (2020). Origins and genetic legacy of prehistoric dogs. in Science
Amer Assoc Advancement Science, Washington., 370(6516), 557-563.
https://doi.org/10.1126/science.aba9572
Bergstrom A, Frantz L, Schmidt R, Ersmark E, Lebrasseur O, Girdland-Flink L, Lin AT, Stora J, Sjogren K, Anthony D, Antipina E, Amiri S, Bar-Oz G, Bazaliiskii VI, Bulatović J, Brown D, Carmagnini A, Davy T, Fedorov S, Fiore I, Fulton D, Germonpre M, Haile J, Irving-Pease EK, Jamieson A, Janssens L, Kirillova I, Horwitz LK, Kuzmanović-Cvetković J, Kuzmin Y, Losey RJ, Loznjak-Dizdar D, Mashkour M, Novak M, Onar V, Orton D, Pasaric M, Radivojević M, Rajković D, Roberts B, Ryan H, Sablin M, Shidlovskiy F, Dimitrijević I, Tagliacozzo A, Trantalidou K, Ullen I, Villaluenga A, Wapnish P, Dobney K, Gotherstrom A, Linderholm A, Dalen L, Pinhasi R, Larson G, Skoglund P. Origins and genetic legacy of prehistoric dogs. in Science. 2020;370(6516):557-563.
doi:10.1126/science.aba9572 .
