Genome-wide analysis of 67 ancient Near Eastern cattle, Bos taurus, remains reveals regional variation that has since been obscured by admixture in modern populations. Comparisons of genomes of early domestic cattle to their aurochs progenitors identify diverse origins with separate introgressions of wild stock. A later region-wide Bronze Age shift indicates rapid and widespread introgression of zebu, Bos indicus, from the Indus Valley. This process was likely stimulated at the onset of the current geological age, similar to 4.2 thousand years ago, by a widespread multicentury drought. In contrast to genome-wide admixture, mitochondrial DNA stasis supports that this introgression was male-driven, suggesting that selection of arid-adapted zebu bulls enhanced herd survival. This human-mediated migration of zebu-derived genetics has continued through millennia, altering tropical herding on each continent.
Source:
Science, 2019, 365, 6449, 173-+
Publisher:
Amer Assoc Advancement Science, Washington
Funding / projects:
ERC Investigator grant [295729-CodeX]
Science Foundation IrelandScience Foundation IrelandEuropean Commission [12/ERC/B2227]
SFI/HEA Irish Centre for High-End Computing (ICHEC)Science Foundation Ireland
Marie Sklodowska-Curie Individual Fellowship H2020-MSCA-IF-2016 [747424]
NERCUK Research & Innovation (UKRI)Natural Environment Research Council (NERC) [NE/P012574/1]
HERA Joint Research Programme "Uses of the Past" (CitiGen)
TY - JOUR
AU - Verdugo, Marta Pereira
AU - Mullin, Victoria E.
AU - Scheu, Amelie
AU - Mattiangeli, Valeria
AU - Daly, Kevin G.
AU - Delser, Pierpaolo Maisano
AU - Hare, Andrew J.
AU - Burger, Joachim
AU - Collins, Matthew J.
AU - Kehati, Ron
AU - Hesse, Paula
AU - Fulton, Deirdre
AU - Sauer, Eberhard W.
AU - Mohaseb, Fatemeh A.
AU - Davoudi, Hossein
AU - Khazaeli, Roya
AU - Lhuillier, Johanna
AU - Rapin, Claude
AU - Ebrahimi, Saeed
AU - Khasanov, Mutalib
AU - Vahidi, S. M. Farhad
AU - MacHugh, David E.
AU - Ertugrul, Okan
AU - Koukouli-Chrysanthaki, Chaido
AU - Sampson, Adamantios
AU - Kazantzis, George
AU - Kontopoulos, Ioannis
AU - Bulatović, Jelena
AU - Dimitrijević, Ivana
AU - Mikdad, Abdesalam
AU - Benecke, Norbert
AU - Linstaedter, Joerg
AU - Sablin, Mikhail
AU - Bendrey, Robin
AU - Gourichon, Lionel
AU - Arbuckle, Benjamin S.
AU - Mashkour, Marjan
AU - Orton, David
AU - Horwitz, Liora Kolska
AU - Teasdale, Matthew D.
AU - Bradley, Daniel G.
PY - 2019
UR - http://rai.ai.ac.rs/handle/123456789/311
AB - Genome-wide analysis of 67 ancient Near Eastern cattle, Bos taurus, remains reveals regional variation that has since been obscured by admixture in modern populations. Comparisons of genomes of early domestic cattle to their aurochs progenitors identify diverse origins with separate introgressions of wild stock. A later region-wide Bronze Age shift indicates rapid and widespread introgression of zebu, Bos indicus, from the Indus Valley. This process was likely stimulated at the onset of the current geological age, similar to 4.2 thousand years ago, by a widespread multicentury drought. In contrast to genome-wide admixture, mitochondrial DNA stasis supports that this introgression was male-driven, suggesting that selection of arid-adapted zebu bulls enhanced herd survival. This human-mediated migration of zebu-derived genetics has continued through millennia, altering tropical herding on each continent.
PB - Amer Assoc Advancement Science, Washington
T2 - Science
T1 - Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent
EP - +
IS - 6449
SP - 173
VL - 365
DO - 10.1126/science.aav1002
UR - conv_352
ER -
@article{
author = "Verdugo, Marta Pereira and Mullin, Victoria E. and Scheu, Amelie and Mattiangeli, Valeria and Daly, Kevin G. and Delser, Pierpaolo Maisano and Hare, Andrew J. and Burger, Joachim and Collins, Matthew J. and Kehati, Ron and Hesse, Paula and Fulton, Deirdre and Sauer, Eberhard W. and Mohaseb, Fatemeh A. and Davoudi, Hossein and Khazaeli, Roya and Lhuillier, Johanna and Rapin, Claude and Ebrahimi, Saeed and Khasanov, Mutalib and Vahidi, S. M. Farhad and MacHugh, David E. and Ertugrul, Okan and Koukouli-Chrysanthaki, Chaido and Sampson, Adamantios and Kazantzis, George and Kontopoulos, Ioannis and Bulatović, Jelena and Dimitrijević, Ivana and Mikdad, Abdesalam and Benecke, Norbert and Linstaedter, Joerg and Sablin, Mikhail and Bendrey, Robin and Gourichon, Lionel and Arbuckle, Benjamin S. and Mashkour, Marjan and Orton, David and Horwitz, Liora Kolska and Teasdale, Matthew D. and Bradley, Daniel G.",
year = "2019",
abstract = "Genome-wide analysis of 67 ancient Near Eastern cattle, Bos taurus, remains reveals regional variation that has since been obscured by admixture in modern populations. Comparisons of genomes of early domestic cattle to their aurochs progenitors identify diverse origins with separate introgressions of wild stock. A later region-wide Bronze Age shift indicates rapid and widespread introgression of zebu, Bos indicus, from the Indus Valley. This process was likely stimulated at the onset of the current geological age, similar to 4.2 thousand years ago, by a widespread multicentury drought. In contrast to genome-wide admixture, mitochondrial DNA stasis supports that this introgression was male-driven, suggesting that selection of arid-adapted zebu bulls enhanced herd survival. This human-mediated migration of zebu-derived genetics has continued through millennia, altering tropical herding on each continent.",
publisher = "Amer Assoc Advancement Science, Washington",
journal = "Science",
title = "Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent",
pages = "+-173",
number = "6449",
volume = "365",
doi = "10.1126/science.aav1002",
url = "conv_352"
}
Verdugo, M. P., Mullin, V. E., Scheu, A., Mattiangeli, V., Daly, K. G., Delser, P. M., Hare, A. J., Burger, J., Collins, M. J., Kehati, R., Hesse, P., Fulton, D., Sauer, E. W., Mohaseb, F. A., Davoudi, H., Khazaeli, R., Lhuillier, J., Rapin, C., Ebrahimi, S., Khasanov, M., Vahidi, S. M. F., MacHugh, D. E., Ertugrul, O., Koukouli-Chrysanthaki, C., Sampson, A., Kazantzis, G., Kontopoulos, I., Bulatović, J., Dimitrijević, I., Mikdad, A., Benecke, N., Linstaedter, J., Sablin, M., Bendrey, R., Gourichon, L., Arbuckle, B. S., Mashkour, M., Orton, D., Horwitz, L. K., Teasdale, M. D.,& Bradley, D. G.. (2019). Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent. in Science
Amer Assoc Advancement Science, Washington., 365(6449), 173-+.
https://doi.org/10.1126/science.aav1002
conv_352
Verdugo MP, Mullin VE, Scheu A, Mattiangeli V, Daly KG, Delser PM, Hare AJ, Burger J, Collins MJ, Kehati R, Hesse P, Fulton D, Sauer EW, Mohaseb FA, Davoudi H, Khazaeli R, Lhuillier J, Rapin C, Ebrahimi S, Khasanov M, Vahidi SMF, MacHugh DE, Ertugrul O, Koukouli-Chrysanthaki C, Sampson A, Kazantzis G, Kontopoulos I, Bulatović J, Dimitrijević I, Mikdad A, Benecke N, Linstaedter J, Sablin M, Bendrey R, Gourichon L, Arbuckle BS, Mashkour M, Orton D, Horwitz LK, Teasdale MD, Bradley DG. Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent. in Science. 2019;365(6449):173-+.
doi:10.1126/science.aav1002
conv_352 .
Verdugo, Marta Pereira, Mullin, Victoria E., Scheu, Amelie, Mattiangeli, Valeria, Daly, Kevin G., Delser, Pierpaolo Maisano, Hare, Andrew J., Burger, Joachim, Collins, Matthew J., Kehati, Ron, Hesse, Paula, Fulton, Deirdre, Sauer, Eberhard W., Mohaseb, Fatemeh A., Davoudi, Hossein, Khazaeli, Roya, Lhuillier, Johanna, Rapin, Claude, Ebrahimi, Saeed, Khasanov, Mutalib, Vahidi, S. M. Farhad, MacHugh, David E., Ertugrul, Okan, Koukouli-Chrysanthaki, Chaido, Sampson, Adamantios, Kazantzis, George, Kontopoulos, Ioannis, Bulatović, Jelena, Dimitrijević, Ivana, Mikdad, Abdesalam, Benecke, Norbert, Linstaedter, Joerg, Sablin, Mikhail, Bendrey, Robin, Gourichon, Lionel, Arbuckle, Benjamin S., Mashkour, Marjan, Orton, David, Horwitz, Liora Kolska, Teasdale, Matthew D., Bradley, Daniel G., "Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent" in Science, 365, no. 6449 (2019):173-+,
https://doi.org/10.1126/science.aav1002 .,
conv_352 .
