Mashkour, Marjan

Link to this page

Authority KeyName Variants
orcid::0000-0003-3630-9459
  • Mashkour, Marjan (3)
Projects
AHRCUK Research & Innovation (UKRI)Arts & Humanities Research Council (AHRC) [AH/J001406/1] [DNRF128]
ERCEuropean Research Council (ERC)European Commission [ERC-2013-StG-337574-UNDEAD] ERC Investigator grant [295729-CodeX]
Erik Philip Sorensen Foundation ESRCUK Research & Innovation (UKRI)Economic & Social Research Council (ESRC) [ES/P010849/1] Funding Source: UKRI
European Research CouncilEuropean Research Council (ERC)European Commission [852558] European UnionEuropean Commission [649307]
Francis Crick Institute from Cancer Research UK [FC001595] HERA Joint Research Programme "Uses of the Past" (CitiGen)
Marie Sklodowska-Curie Individual Fellowship H2020-MSCA-IF-2016 [747424] Natural Environmental Research CouncilUK Research & Innovation (UKRI)Natural Environment Research Council (NERC) [NE/K005243/1, NE/K003259/1]
NERC Radiocarbon FacilityUK Research & Innovation (UKRI)Natural Environment Research Council (NERC) [NF/2016/2/4] NERCUK Research & Innovation (UKRI)Natural Environment Research Council (NERC) [NE/K003259/2, NE/K005243/2, NE/K005243/1] Funding Source: UKRI
NERCUK Research & Innovation (UKRI)Natural Environment Research Council (NERC) [NE/P012574/1] Science Foundation IrelandScience Foundation IrelandEuropean Commission [12/ERC/B2227]
SciLifeLab National Projects SFI/HEA Irish Centre for High-End Computing (ICHEC)Science Foundation Ireland
Smithsonian's Peter Buck Postdoctoral Fellowship SNIC-UPPMAX [b2016004]
Social Sciences and Humanities Research Council of CanadaSocial Sciences and Humanities Research Council of Canada (SSHRC) [SSHRC IG 435-2014-0075] State Assignment of the Sobolev Institute of Geology and Mineralogy
Trinseq UK Medical Research CouncilUK Research & Innovation (UKRI)Medical Research Council UK (MRC)
UOXF ARC facilityAustralian Research Council Vallee Foundation
Wellcome Trust Investigator awardWellcome Trust [217223/Z/19/Z] Wellcome TrustWellcome TrustEuropean Commission [210119/Z/18/Z]
Wolfson College (University of Oxford) ZIN RAS [AAA-A19119032590102-7]

Author's Bibliography

Ancient chicken remains reveal the origins of virulence in Marek’s disease virus

Fiddaman, Steven R.; Dimopoulos, Evangelos A.; Lebrasseur, Ophélie; du Plessis, Louis; Vrancken, Bram; Charlton, Sophy; Haruda, Ashleigh F.; Tabbada, Kristina; Flammer, Patrik G.; Dascalu, Stefan; Marković, Nemanja; Li, Hannah; Franklin, Gabrielle; Symmons, Robert; Baron, Henriette; Daróczi-Szabó, László; Shaymuratova, Dilyara N.; Askeyev, Igor V.; Putelat, Olivier; Sana, Maria; Davoudi, Hossein; Fathi, Homa; Mucheshi, Amir Saed; Vahdati, Ali Akbar; Zhang, Liangren; Foster, Alison; Sykes, Naomi; Baumberg, Gabrielle Cass; Bulatović, Jelena; Askeyev, Arthur O.; Askeyev, Oleg V.; Mashkour, Marjan; Pybus, Oliver G.; Nair, Venugopal; Larson, Greger; Smith, Adrian L.; Frantz, Laurent A. F.

(American Association for the Advancement of Science (AAAS), 2023)

TY  - JOUR
AU  - Fiddaman, Steven R.
AU  - Dimopoulos, Evangelos A.
AU  - Lebrasseur, Ophélie
AU  - du Plessis, Louis
AU  - Vrancken, Bram
AU  - Charlton, Sophy
AU  - Haruda, Ashleigh F.
AU  - Tabbada, Kristina
AU  - Flammer, Patrik G.
AU  - Dascalu, Stefan
AU  - Marković, Nemanja
AU  - Li, Hannah
AU  - Franklin, Gabrielle
AU  - Symmons, Robert
AU  - Baron, Henriette
AU  - Daróczi-Szabó, László
AU  - Shaymuratova, Dilyara N.
AU  - Askeyev, Igor V.
AU  - Putelat, Olivier
AU  - Sana, Maria
AU  - Davoudi, Hossein
AU  - Fathi, Homa
AU  - Mucheshi, Amir Saed
AU  - Vahdati, Ali Akbar
AU  - Zhang, Liangren
AU  - Foster, Alison
AU  - Sykes, Naomi
AU  - Baumberg, Gabrielle Cass
AU  - Bulatović, Jelena
AU  - Askeyev, Arthur O.
AU  - Askeyev, Oleg V.
AU  - Mashkour, Marjan
AU  - Pybus, Oliver G.
AU  - Nair, Venugopal
AU  - Larson, Greger
AU  - Smith, Adrian L.
AU  - Frantz, Laurent A. F.
PY  - 2023
UR  - http://rai.ai.ac.rs/handle/123456789/1134
AB  - The pronounced growth in livestock populations since the 1950s has altered the epidemiological and evolutionary trajectory of their associated pathogens. For example, Marek’s disease virus (MDV), which causes lymphoid tumors in chickens, has experienced a marked increase in virulence over the past century. Today, MDV infections kill >90% of unvaccinated birds, and controlling it costs more than US$1 billion annually. By sequencing MDV genomes derived from archeological chickens, we demonstrate that it has been circulating for at least 1000 years. We functionally tested the Meq oncogene, one of 49 viral genes positively selected in modern strains, demonstrating that ancient MDV was likely incapable of driving tumor formation. Our results demonstrate the power of ancient DNA approaches to trace the molecular basis of virulence in economically relevant pathogens.
PB  - American Association for the Advancement of Science (AAAS)
T2  - Science
T1  - Ancient chicken remains reveal the origins of virulence in Marek’s disease virus
EP  - 1281
IS  - 6676
SP  - 1276
VL  - 382
DO  - 10.1126/science.adg2238
ER  - 
@article{
author = "Fiddaman, Steven R. and Dimopoulos, Evangelos A. and Lebrasseur, Ophélie and du Plessis, Louis and Vrancken, Bram and Charlton, Sophy and Haruda, Ashleigh F. and Tabbada, Kristina and Flammer, Patrik G. and Dascalu, Stefan and Marković, Nemanja and Li, Hannah and Franklin, Gabrielle and Symmons, Robert and Baron, Henriette and Daróczi-Szabó, László and Shaymuratova, Dilyara N. and Askeyev, Igor V. and Putelat, Olivier and Sana, Maria and Davoudi, Hossein and Fathi, Homa and Mucheshi, Amir Saed and Vahdati, Ali Akbar and Zhang, Liangren and Foster, Alison and Sykes, Naomi and Baumberg, Gabrielle Cass and Bulatović, Jelena and Askeyev, Arthur O. and Askeyev, Oleg V. and Mashkour, Marjan and Pybus, Oliver G. and Nair, Venugopal and Larson, Greger and Smith, Adrian L. and Frantz, Laurent A. F.",
year = "2023",
abstract = "The pronounced growth in livestock populations since the 1950s has altered the epidemiological and evolutionary trajectory of their associated pathogens. For example, Marek’s disease virus (MDV), which causes lymphoid tumors in chickens, has experienced a marked increase in virulence over the past century. Today, MDV infections kill >90% of unvaccinated birds, and controlling it costs more than US$1 billion annually. By sequencing MDV genomes derived from archeological chickens, we demonstrate that it has been circulating for at least 1000 years. We functionally tested the Meq oncogene, one of 49 viral genes positively selected in modern strains, demonstrating that ancient MDV was likely incapable of driving tumor formation. Our results demonstrate the power of ancient DNA approaches to trace the molecular basis of virulence in economically relevant pathogens.",
publisher = "American Association for the Advancement of Science (AAAS)",
journal = "Science",
title = "Ancient chicken remains reveal the origins of virulence in Marek’s disease virus",
pages = "1281-1276",
number = "6676",
volume = "382",
doi = "10.1126/science.adg2238"
}
Fiddaman, S. R., Dimopoulos, E. A., Lebrasseur, O., du Plessis, L., Vrancken, B., Charlton, S., Haruda, A. F., Tabbada, K., Flammer, P. G., Dascalu, S., Marković, N., Li, H., Franklin, G., Symmons, R., Baron, H., Daróczi-Szabó, L., Shaymuratova, D. N., Askeyev, I. V., Putelat, O., Sana, M., Davoudi, H., Fathi, H., Mucheshi, A. S., Vahdati, A. A., Zhang, L., Foster, A., Sykes, N., Baumberg, G. C., Bulatović, J., Askeyev, A. O., Askeyev, O. V., Mashkour, M., Pybus, O. G., Nair, V., Larson, G., Smith, A. L.,& Frantz, L. A. F.. (2023). Ancient chicken remains reveal the origins of virulence in Marek’s disease virus. in Science
American Association for the Advancement of Science (AAAS)., 382(6676), 1276-1281.
https://doi.org/10.1126/science.adg2238
Fiddaman SR, Dimopoulos EA, Lebrasseur O, du Plessis L, Vrancken B, Charlton S, Haruda AF, Tabbada K, Flammer PG, Dascalu S, Marković N, Li H, Franklin G, Symmons R, Baron H, Daróczi-Szabó L, Shaymuratova DN, Askeyev IV, Putelat O, Sana M, Davoudi H, Fathi H, Mucheshi AS, Vahdati AA, Zhang L, Foster A, Sykes N, Baumberg GC, Bulatović J, Askeyev AO, Askeyev OV, Mashkour M, Pybus OG, Nair V, Larson G, Smith AL, Frantz LAF. Ancient chicken remains reveal the origins of virulence in Marek’s disease virus. in Science. 2023;382(6676):1276-1281.
doi:10.1126/science.adg2238 .
Fiddaman, Steven R., Dimopoulos, Evangelos A., Lebrasseur, Ophélie, du Plessis, Louis, Vrancken, Bram, Charlton, Sophy, Haruda, Ashleigh F., Tabbada, Kristina, Flammer, Patrik G., Dascalu, Stefan, Marković, Nemanja, Li, Hannah, Franklin, Gabrielle, Symmons, Robert, Baron, Henriette, Daróczi-Szabó, László, Shaymuratova, Dilyara N., Askeyev, Igor V., Putelat, Olivier, Sana, Maria, Davoudi, Hossein, Fathi, Homa, Mucheshi, Amir Saed, Vahdati, Ali Akbar, Zhang, Liangren, Foster, Alison, Sykes, Naomi, Baumberg, Gabrielle Cass, Bulatović, Jelena, Askeyev, Arthur O., Askeyev, Oleg V., Mashkour, Marjan, Pybus, Oliver G., Nair, Venugopal, Larson, Greger, Smith, Adrian L., Frantz, Laurent A. F., "Ancient chicken remains reveal the origins of virulence in Marek’s disease virus" in Science, 382, no. 6676 (2023):1276-1281,
https://doi.org/10.1126/science.adg2238 . .
395
5

Origins and genetic legacy of prehistoric dogs

Bergstrom, Anders; Frantz, Laurent; Schmidt, Ryan; Ersmark, Erik; Lebrasseur, Ophelie; Girdland-Flink, Linus; Lin, Audrey T.; Stora, Jan; Sjogren, Karl-Goran; Anthony, David; Antipina, Ekaterina; Amiri, Sarieh; Bar-Oz, Guy; Bazaliiskii, Vladimir I.; Bulatović, Jelena; Brown, Dorcas; Carmagnini, Alberto; Davy, Tom; Fedorov, Sergey; Fiore, Ivana; Fulton, Deirdre; Germonpre, Mietje; Haile, James; Irving-Pease, Evan K.; Jamieson, Alexandra; Janssens, Luc; Kirillova, Irina; Horwitz, Liora Kolska; Kuzmanović-Cvetković, Julka; Kuzmin, Yaroslav; Losey, Robert J.; Loznjak-Dizdar, Daria; Mashkour, Marjan; Novak, Mario; Onar, Vedat; Orton, David; Pasaric, Maja; Radivojević, Miljana; Rajković, Dragana; Roberts, Benjamin; Ryan, Hannah; Sablin, Mikhail; Shidlovskiy, Fedor; Dimitrijević, Ivana; Tagliacozzo, Antonio; Trantalidou, Katerina; Ullen, Inga; Villaluenga, Aritza; Wapnish, Paula; Dobney, Keith; Gotherstrom, Anders; Linderholm, Anna; Dalen, Love; Pinhasi, Ron; Larson, Greger; Skoglund, Pontus

(Amer Assoc Advancement Science, Washington, 2020)

TY  - JOUR
AU  - Bergstrom, Anders
AU  - Frantz, Laurent
AU  - Schmidt, Ryan
AU  - Ersmark, Erik
AU  - Lebrasseur, Ophelie
AU  - Girdland-Flink, Linus
AU  - Lin, Audrey T.
AU  - Stora, Jan
AU  - Sjogren, Karl-Goran
AU  - Anthony, David
AU  - Antipina, Ekaterina
AU  - Amiri, Sarieh
AU  - Bar-Oz, Guy
AU  - Bazaliiskii, Vladimir I.
AU  - Bulatović, Jelena
AU  - Brown, Dorcas
AU  - Carmagnini, Alberto
AU  - Davy, Tom
AU  - Fedorov, Sergey
AU  - Fiore, Ivana
AU  - Fulton, Deirdre
AU  - Germonpre, Mietje
AU  - Haile, James
AU  - Irving-Pease, Evan K.
AU  - Jamieson, Alexandra
AU  - Janssens, Luc
AU  - Kirillova, Irina
AU  - Horwitz, Liora Kolska
AU  - Kuzmanović-Cvetković, Julka
AU  - Kuzmin, Yaroslav
AU  - Losey, Robert J.
AU  - Loznjak-Dizdar, Daria
AU  - Mashkour, Marjan
AU  - Novak, Mario
AU  - Onar, Vedat
AU  - Orton, David
AU  - Pasaric, Maja
AU  - Radivojević, Miljana
AU  - Rajković, Dragana
AU  - Roberts, Benjamin
AU  - Ryan, Hannah
AU  - Sablin, Mikhail
AU  - Shidlovskiy, Fedor
AU  - Dimitrijević, Ivana
AU  - Tagliacozzo, Antonio
AU  - Trantalidou, Katerina
AU  - Ullen, Inga
AU  - Villaluenga, Aritza
AU  - Wapnish, Paula
AU  - Dobney, Keith
AU  - Gotherstrom, Anders
AU  - Linderholm, Anna
AU  - Dalen, Love
AU  - Pinhasi, Ron
AU  - Larson, Greger
AU  - Skoglund, Pontus
PY  - 2020
UR  - http://rai.ai.ac.rs/handle/123456789/353
AB  - Dogs were the first domestic animal, but little is known about their population history and to what extent it was linked to humans. We sequenced 27 ancient dog genomes and found that all dogs share a common ancestry distinct from present-day wolves, with limited gene flow from wolves since domestication but substantial dog-to-wolf gene flow. By 11,000 years ago, at least five major ancestry lineages had diversified, demonstrating a deep genetic history of dogs during the Paleolithic. Coanalysis with human genomes reveals aspects of dog population history that mirror humans, including Levant-related ancestry in Africa and early agricultural Europe. Other aspects differ, including the impacts of steppe pastoralist expansions in West and East Eurasia and a near-complete turnover of Neolithic European dog ancestry.
PB  - Amer Assoc Advancement Science, Washington
T2  - Science
T1  - Origins and genetic legacy of prehistoric dogs
EP  - 563
IS  - 6516
SP  - 557
VL  - 370
DO  - 10.1126/science.aba9572
ER  - 
@article{
author = "Bergstrom, Anders and Frantz, Laurent and Schmidt, Ryan and Ersmark, Erik and Lebrasseur, Ophelie and Girdland-Flink, Linus and Lin, Audrey T. and Stora, Jan and Sjogren, Karl-Goran and Anthony, David and Antipina, Ekaterina and Amiri, Sarieh and Bar-Oz, Guy and Bazaliiskii, Vladimir I. and Bulatović, Jelena and Brown, Dorcas and Carmagnini, Alberto and Davy, Tom and Fedorov, Sergey and Fiore, Ivana and Fulton, Deirdre and Germonpre, Mietje and Haile, James and Irving-Pease, Evan K. and Jamieson, Alexandra and Janssens, Luc and Kirillova, Irina and Horwitz, Liora Kolska and Kuzmanović-Cvetković, Julka and Kuzmin, Yaroslav and Losey, Robert J. and Loznjak-Dizdar, Daria and Mashkour, Marjan and Novak, Mario and Onar, Vedat and Orton, David and Pasaric, Maja and Radivojević, Miljana and Rajković, Dragana and Roberts, Benjamin and Ryan, Hannah and Sablin, Mikhail and Shidlovskiy, Fedor and Dimitrijević, Ivana and Tagliacozzo, Antonio and Trantalidou, Katerina and Ullen, Inga and Villaluenga, Aritza and Wapnish, Paula and Dobney, Keith and Gotherstrom, Anders and Linderholm, Anna and Dalen, Love and Pinhasi, Ron and Larson, Greger and Skoglund, Pontus",
year = "2020",
abstract = "Dogs were the first domestic animal, but little is known about their population history and to what extent it was linked to humans. We sequenced 27 ancient dog genomes and found that all dogs share a common ancestry distinct from present-day wolves, with limited gene flow from wolves since domestication but substantial dog-to-wolf gene flow. By 11,000 years ago, at least five major ancestry lineages had diversified, demonstrating a deep genetic history of dogs during the Paleolithic. Coanalysis with human genomes reveals aspects of dog population history that mirror humans, including Levant-related ancestry in Africa and early agricultural Europe. Other aspects differ, including the impacts of steppe pastoralist expansions in West and East Eurasia and a near-complete turnover of Neolithic European dog ancestry.",
publisher = "Amer Assoc Advancement Science, Washington",
journal = "Science",
title = "Origins and genetic legacy of prehistoric dogs",
pages = "563-557",
number = "6516",
volume = "370",
doi = "10.1126/science.aba9572"
}
Bergstrom, A., Frantz, L., Schmidt, R., Ersmark, E., Lebrasseur, O., Girdland-Flink, L., Lin, A. T., Stora, J., Sjogren, K., Anthony, D., Antipina, E., Amiri, S., Bar-Oz, G., Bazaliiskii, V. I., Bulatović, J., Brown, D., Carmagnini, A., Davy, T., Fedorov, S., Fiore, I., Fulton, D., Germonpre, M., Haile, J., Irving-Pease, E. K., Jamieson, A., Janssens, L., Kirillova, I., Horwitz, L. K., Kuzmanović-Cvetković, J., Kuzmin, Y., Losey, R. J., Loznjak-Dizdar, D., Mashkour, M., Novak, M., Onar, V., Orton, D., Pasaric, M., Radivojević, M., Rajković, D., Roberts, B., Ryan, H., Sablin, M., Shidlovskiy, F., Dimitrijević, I., Tagliacozzo, A., Trantalidou, K., Ullen, I., Villaluenga, A., Wapnish, P., Dobney, K., Gotherstrom, A., Linderholm, A., Dalen, L., Pinhasi, R., Larson, G.,& Skoglund, P.. (2020). Origins and genetic legacy of prehistoric dogs. in Science
Amer Assoc Advancement Science, Washington., 370(6516), 557-563.
https://doi.org/10.1126/science.aba9572
Bergstrom A, Frantz L, Schmidt R, Ersmark E, Lebrasseur O, Girdland-Flink L, Lin AT, Stora J, Sjogren K, Anthony D, Antipina E, Amiri S, Bar-Oz G, Bazaliiskii VI, Bulatović J, Brown D, Carmagnini A, Davy T, Fedorov S, Fiore I, Fulton D, Germonpre M, Haile J, Irving-Pease EK, Jamieson A, Janssens L, Kirillova I, Horwitz LK, Kuzmanović-Cvetković J, Kuzmin Y, Losey RJ, Loznjak-Dizdar D, Mashkour M, Novak M, Onar V, Orton D, Pasaric M, Radivojević M, Rajković D, Roberts B, Ryan H, Sablin M, Shidlovskiy F, Dimitrijević I, Tagliacozzo A, Trantalidou K, Ullen I, Villaluenga A, Wapnish P, Dobney K, Gotherstrom A, Linderholm A, Dalen L, Pinhasi R, Larson G, Skoglund P. Origins and genetic legacy of prehistoric dogs. in Science. 2020;370(6516):557-563.
doi:10.1126/science.aba9572 .
Bergstrom, Anders, Frantz, Laurent, Schmidt, Ryan, Ersmark, Erik, Lebrasseur, Ophelie, Girdland-Flink, Linus, Lin, Audrey T., Stora, Jan, Sjogren, Karl-Goran, Anthony, David, Antipina, Ekaterina, Amiri, Sarieh, Bar-Oz, Guy, Bazaliiskii, Vladimir I., Bulatović, Jelena, Brown, Dorcas, Carmagnini, Alberto, Davy, Tom, Fedorov, Sergey, Fiore, Ivana, Fulton, Deirdre, Germonpre, Mietje, Haile, James, Irving-Pease, Evan K., Jamieson, Alexandra, Janssens, Luc, Kirillova, Irina, Horwitz, Liora Kolska, Kuzmanović-Cvetković, Julka, Kuzmin, Yaroslav, Losey, Robert J., Loznjak-Dizdar, Daria, Mashkour, Marjan, Novak, Mario, Onar, Vedat, Orton, David, Pasaric, Maja, Radivojević, Miljana, Rajković, Dragana, Roberts, Benjamin, Ryan, Hannah, Sablin, Mikhail, Shidlovskiy, Fedor, Dimitrijević, Ivana, Tagliacozzo, Antonio, Trantalidou, Katerina, Ullen, Inga, Villaluenga, Aritza, Wapnish, Paula, Dobney, Keith, Gotherstrom, Anders, Linderholm, Anna, Dalen, Love, Pinhasi, Ron, Larson, Greger, Skoglund, Pontus, "Origins and genetic legacy of prehistoric dogs" in Science, 370, no. 6516 (2020):557-563,
https://doi.org/10.1126/science.aba9572 . .
2972
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1
124

Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent

Verdugo, Marta Pereira; Mullin, Victoria E.; Scheu, Amelie; Mattiangeli, Valeria; Daly, Kevin G.; Delser, Pierpaolo Maisano; Hare, Andrew J.; Burger, Joachim; Collins, Matthew J.; Kehati, Ron; Hesse, Paula; Fulton, Deirdre; Sauer, Eberhard W.; Mohaseb, Fatemeh A.; Davoudi, Hossein; Khazaeli, Roya; Lhuillier, Johanna; Rapin, Claude; Ebrahimi, Saeed; Khasanov, Mutalib; Vahidi, S. M. Farhad; MacHugh, David E.; Ertugrul, Okan; Koukouli-Chrysanthaki, Chaido; Sampson, Adamantios; Kazantzis, George; Kontopoulos, Ioannis; Bulatović, Jelena; Dimitrijević, Ivana; Mikdad, Abdesalam; Benecke, Norbert; Linstaedter, Joerg; Sablin, Mikhail; Bendrey, Robin; Gourichon, Lionel; Arbuckle, Benjamin S.; Mashkour, Marjan; Orton, David; Horwitz, Liora Kolska; Teasdale, Matthew D.; Bradley, Daniel G.

(Amer Assoc Advancement Science, Washington, 2019)

TY  - JOUR
AU  - Verdugo, Marta Pereira
AU  - Mullin, Victoria E.
AU  - Scheu, Amelie
AU  - Mattiangeli, Valeria
AU  - Daly, Kevin G.
AU  - Delser, Pierpaolo Maisano
AU  - Hare, Andrew J.
AU  - Burger, Joachim
AU  - Collins, Matthew J.
AU  - Kehati, Ron
AU  - Hesse, Paula
AU  - Fulton, Deirdre
AU  - Sauer, Eberhard W.
AU  - Mohaseb, Fatemeh A.
AU  - Davoudi, Hossein
AU  - Khazaeli, Roya
AU  - Lhuillier, Johanna
AU  - Rapin, Claude
AU  - Ebrahimi, Saeed
AU  - Khasanov, Mutalib
AU  - Vahidi, S. M. Farhad
AU  - MacHugh, David E.
AU  - Ertugrul, Okan
AU  - Koukouli-Chrysanthaki, Chaido
AU  - Sampson, Adamantios
AU  - Kazantzis, George
AU  - Kontopoulos, Ioannis
AU  - Bulatović, Jelena
AU  - Dimitrijević, Ivana
AU  - Mikdad, Abdesalam
AU  - Benecke, Norbert
AU  - Linstaedter, Joerg
AU  - Sablin, Mikhail
AU  - Bendrey, Robin
AU  - Gourichon, Lionel
AU  - Arbuckle, Benjamin S.
AU  - Mashkour, Marjan
AU  - Orton, David
AU  - Horwitz, Liora Kolska
AU  - Teasdale, Matthew D.
AU  - Bradley, Daniel G.
PY  - 2019
UR  - http://rai.ai.ac.rs/handle/123456789/311
AB  - Genome-wide analysis of 67 ancient Near Eastern cattle, Bos taurus, remains reveals regional variation that has since been obscured by admixture in modern populations. Comparisons of genomes of early domestic cattle to their aurochs progenitors identify diverse origins with separate introgressions of wild stock. A later region-wide Bronze Age shift indicates rapid and widespread introgression of zebu, Bos indicus, from the Indus Valley. This process was likely stimulated at the onset of the current geological age, similar to 4.2 thousand years ago, by a widespread multicentury drought. In contrast to genome-wide admixture, mitochondrial DNA stasis supports that this introgression was male-driven, suggesting that selection of arid-adapted zebu bulls enhanced herd survival. This human-mediated migration of zebu-derived genetics has continued through millennia, altering tropical herding on each continent.
PB  - Amer Assoc Advancement Science, Washington
T2  - Science
T1  - Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent
EP  - +
IS  - 6449
SP  - 173
VL  - 365
DO  - 10.1126/science.aav1002
ER  - 
@article{
author = "Verdugo, Marta Pereira and Mullin, Victoria E. and Scheu, Amelie and Mattiangeli, Valeria and Daly, Kevin G. and Delser, Pierpaolo Maisano and Hare, Andrew J. and Burger, Joachim and Collins, Matthew J. and Kehati, Ron and Hesse, Paula and Fulton, Deirdre and Sauer, Eberhard W. and Mohaseb, Fatemeh A. and Davoudi, Hossein and Khazaeli, Roya and Lhuillier, Johanna and Rapin, Claude and Ebrahimi, Saeed and Khasanov, Mutalib and Vahidi, S. M. Farhad and MacHugh, David E. and Ertugrul, Okan and Koukouli-Chrysanthaki, Chaido and Sampson, Adamantios and Kazantzis, George and Kontopoulos, Ioannis and Bulatović, Jelena and Dimitrijević, Ivana and Mikdad, Abdesalam and Benecke, Norbert and Linstaedter, Joerg and Sablin, Mikhail and Bendrey, Robin and Gourichon, Lionel and Arbuckle, Benjamin S. and Mashkour, Marjan and Orton, David and Horwitz, Liora Kolska and Teasdale, Matthew D. and Bradley, Daniel G.",
year = "2019",
abstract = "Genome-wide analysis of 67 ancient Near Eastern cattle, Bos taurus, remains reveals regional variation that has since been obscured by admixture in modern populations. Comparisons of genomes of early domestic cattle to their aurochs progenitors identify diverse origins with separate introgressions of wild stock. A later region-wide Bronze Age shift indicates rapid and widespread introgression of zebu, Bos indicus, from the Indus Valley. This process was likely stimulated at the onset of the current geological age, similar to 4.2 thousand years ago, by a widespread multicentury drought. In contrast to genome-wide admixture, mitochondrial DNA stasis supports that this introgression was male-driven, suggesting that selection of arid-adapted zebu bulls enhanced herd survival. This human-mediated migration of zebu-derived genetics has continued through millennia, altering tropical herding on each continent.",
publisher = "Amer Assoc Advancement Science, Washington",
journal = "Science",
title = "Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent",
pages = "+-173",
number = "6449",
volume = "365",
doi = "10.1126/science.aav1002"
}
Verdugo, M. P., Mullin, V. E., Scheu, A., Mattiangeli, V., Daly, K. G., Delser, P. M., Hare, A. J., Burger, J., Collins, M. J., Kehati, R., Hesse, P., Fulton, D., Sauer, E. W., Mohaseb, F. A., Davoudi, H., Khazaeli, R., Lhuillier, J., Rapin, C., Ebrahimi, S., Khasanov, M., Vahidi, S. M. F., MacHugh, D. E., Ertugrul, O., Koukouli-Chrysanthaki, C., Sampson, A., Kazantzis, G., Kontopoulos, I., Bulatović, J., Dimitrijević, I., Mikdad, A., Benecke, N., Linstaedter, J., Sablin, M., Bendrey, R., Gourichon, L., Arbuckle, B. S., Mashkour, M., Orton, D., Horwitz, L. K., Teasdale, M. D.,& Bradley, D. G.. (2019). Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent. in Science
Amer Assoc Advancement Science, Washington., 365(6449), 173-+.
https://doi.org/10.1126/science.aav1002
Verdugo MP, Mullin VE, Scheu A, Mattiangeli V, Daly KG, Delser PM, Hare AJ, Burger J, Collins MJ, Kehati R, Hesse P, Fulton D, Sauer EW, Mohaseb FA, Davoudi H, Khazaeli R, Lhuillier J, Rapin C, Ebrahimi S, Khasanov M, Vahidi SMF, MacHugh DE, Ertugrul O, Koukouli-Chrysanthaki C, Sampson A, Kazantzis G, Kontopoulos I, Bulatović J, Dimitrijević I, Mikdad A, Benecke N, Linstaedter J, Sablin M, Bendrey R, Gourichon L, Arbuckle BS, Mashkour M, Orton D, Horwitz LK, Teasdale MD, Bradley DG. Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent. in Science. 2019;365(6449):173-+.
doi:10.1126/science.aav1002 .
Verdugo, Marta Pereira, Mullin, Victoria E., Scheu, Amelie, Mattiangeli, Valeria, Daly, Kevin G., Delser, Pierpaolo Maisano, Hare, Andrew J., Burger, Joachim, Collins, Matthew J., Kehati, Ron, Hesse, Paula, Fulton, Deirdre, Sauer, Eberhard W., Mohaseb, Fatemeh A., Davoudi, Hossein, Khazaeli, Roya, Lhuillier, Johanna, Rapin, Claude, Ebrahimi, Saeed, Khasanov, Mutalib, Vahidi, S. M. Farhad, MacHugh, David E., Ertugrul, Okan, Koukouli-Chrysanthaki, Chaido, Sampson, Adamantios, Kazantzis, George, Kontopoulos, Ioannis, Bulatović, Jelena, Dimitrijević, Ivana, Mikdad, Abdesalam, Benecke, Norbert, Linstaedter, Joerg, Sablin, Mikhail, Bendrey, Robin, Gourichon, Lionel, Arbuckle, Benjamin S., Mashkour, Marjan, Orton, David, Horwitz, Liora Kolska, Teasdale, Matthew D., Bradley, Daniel G., "Ancient cattle genomics, origins, and rapid turnover in the Fertile Crescent" in Science, 365, no. 6449 (2019):173-+,
https://doi.org/10.1126/science.aav1002 . .
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